Botulinum Neurotoxin Injections in Childhood Opisthotonus
نویسندگان
چکیده
منابع مشابه
Bone changes in the mandible following botulinum neurotoxin injections.
In this study, botulinum neurotoxin type A (BoTx/A) was injected into the temporalis and masseter muscles of growing rats to induce masticatory hypoactivity. Sixty, 30-day-old, male Long-Evans rats were randomly divided into four groups. BoTx/A was bilaterally injected in the masseter muscles in group I, in the temporalis muscles in group II, and into both the masseter and the temporalis muscle...
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Botulinum neurotoxin type A (BoNT/A) paralyses muscles by blocking acetylcholine (ACh) release from motor nerve terminals. Although highly toxic, it is used clinically to weaken muscles whose contraction is undesirable, as in dystonias. The effects of an injection of BoNT/A wear off after 3-4 months so repeated injections are often used. Recovery of neuromuscular transmission is accompanied by ...
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ژورنال
عنوان ژورنال: Toxins
سال: 2021
ISSN: 2072-6651
DOI: 10.3390/toxins13020137